Our mission
We are a team of creative, ambitious and friendly researchers who investigate membrane transport processes in pathogenic bacteria and develop innovative protein engineering tools. We combine the disciplines of structural biology, binder generation, protein biochemistry and microbiology to uncover molecular details of how membrane transport proteins expel antibiotics, shuttle siderophores and export lipids. Sybodies and NestLink enable us to target membrane transporters in the cellular context to develop rapid diagnostics, novel antibiotics and tailor-made research tools.
Very excited to share our latest published #cryoEM work on the #microsporidian #proteasome with all its proteolytic sites inhibited simultaneously by a PI31-like peptide!! Fantastic job from Nathan, Kai, Rahel, and Dennis, and collaboration with Charlie ( @CT_CAES)! https://t.co/WFxe6NtkTV
From preventive measures in animal production to the monitoring of transmission chains between people and the environment: NRP 72 presents new solutions for combating antibiotic resistance from 45 research projects.
#AMR #AntibioticResistance
https://t.co/kj2jCUbbJ6
#AMR #AntibioticResistance
https://t.co/kj2jCUbbJ6
Job Alert! 🇨đź‡our lab received funding for a part-time Research Assistant position to join us at #UZH_IPT on a new fluorescent sensor development project. Prior experience in molecular cloning is a must. For more details pls see below. Apply! https://t.co/lO3dyOmNYG
We're hiring! Fully funded #Postdoc and #PhD positions to work on in-cell EPR with #nanobody and in-organelle #EPR on Bcl-2 proteins in #apoptosis. EPR with cryo-EM, AI and modeling. Collaborations with @seegerlab @Intein and @gervasiolab
Interested? contact @enricabordignon
Interested? contact @enricabordignon
Very happy to share the final paper of my PhD at @DutzlerLab! Together with @MelanieArndt96, we used electrophysiology, cell-base scrambling assays and cryo-EM to investigate the elusive mechanism of TMEM16F activation.
https://t.co/TzuwxtGFrj
https://t.co/TzuwxtGFrj