We are a team of creative, ambitious and friendly researchers who investigate membrane transport processes in pathogenic bacteria and develop innovative protein engineering tools. We combine the disciplines of structural biology, binder generation, protein biochemistry and microbiology to uncover molecular details of how membrane transport proteins expel antibiotics, shuttle siderophores and export lipids. Sybodies and NestLink enable us to target membrane transporters in the cellular context to develop rapid diagnostics, novel antibiotics and tailor-made research tools.
The latest @PNASNews paper from the @HillerLab and @BumannLab is shaking common assumptions on porins function, which may unravel new ways of facilitating antibiotic delivery. Great collaborative work: https://t.co/wfo0pgdxCl @antibiotic @microbiology @biozentrum @UniBasel
2 days until the EB deadline of #Nanobodies21! Don't miss this 2 day hybrid event (8-9 Sept) followed by Trends in #Structuralbiology (10 Sept). Over 100 submitted abstracts, 3 Workshops & 20 topspeakers in the #Nanobody field: discover all topics here: https://t.co/vA5nmQkgZU https://t.co/ioNNeGg25Z
Last year we presented #AlphaFold v2 which predicts 3D structures of proteins down to atomic accuracy. Today we’re proud to share the methods in @Nature w/open source code. Excited to see the research this enables. More very soon!